Trafficking protein particle complex subunit 4

BE0004278ProteinHumansTRAPPC4

Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable). It is acted on by 1 drug in DrugBank.

Gene name
TRAPPC4
UniProtKB entry
Q9Y296Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
219 residues · 24,340 Da
Also known as
Hematopoietic stem/progenitor cell protein 172 · SBDN · Synbindin · TRS23 homolog

Resolves to

Protein
UniProtQ9Y296UniProt nameTPPC4_HUMAN
Gene
HGNCHGNC:19943NCBI Gene51399GenBank6650543GeneCardsTRAPPC4
Pharmacology
KEGGhsa:51399
Structure
PDB2J3TPDB2JSNPDB2ZMV
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Trafficking protein particle complex subunit 4, and which indications are they being tested in?

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