CAI-1 autoinducer synthase

BE0004287ProteinVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)cqsA

Required for the synthesis of the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal. It is acted on by 1 drug in DrugBank.

Gene name
cqsA
UniProtKB entry
Q9KM65Swiss-Prot
Residues / weight
389 residues · 43,593 Da
Also known as
2.3.-.- · Cholerae quorum-sensing autoinducer

Resolves to

Protein
UniProtQ9KM65UniProt nameCQSA_VIBCH
Gene
NCBI Gene2612753GenBank9657379
Pharmacology
KEGGvch:VCA0523
Structure
PDB2WK7PDB2WK8PDB2WK9
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on CAI-1 autoinducer synthase, and which indications are they being tested in?

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