Rhomboid protease GlpG

BE0004288ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)glpG

Rhomboid-type serine protease that catalyzes intramembrane proteolysis. It is acted on by 1 drug in DrugBank.

Gene name
glpG
UniProtKB entry
P44783Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
192 residues · 21,657 Da
Also known as
3.4.21.105 · Intramembrane serine protease

Resolves to

Protein
UniProtP44783UniProt nameGLPG_HAEIN
Gene
NCBI Gene950685GenBank3212176
Pharmacology
KEGGhin:HI0618
Structure
PDB2NR9PDB3ODJ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Rhomboid protease GlpG, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In