Adenylosuccinate synthetase

BE0004308ProteinYersinia pestispurA

Plays an important role in the de novo pathway of purine nucleotide biosynthesis. It is acted on by 1 drug in DrugBank.

Gene name
purA
UniProtKB entry
Q8ZIV7Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
432 residues · 47,278 Da
Also known as
6.3.4.4 · AMPSase · IMP--aspartate ligase

Resolves to

Protein
UniProtQ8ZIV7UniProt namePURA_YERPE
Gene
NCBI Gene1173224GenBank115345833
Pharmacology
KEGGype:YPO0378
Structure
PDB3HID
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Adenylosuccinate synthetase, and which indications are they being tested in?

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