TetR family transcriptional repressor LfrR

BE0004319ProteinMycobacterium smegmatislfrR

TetR family transcriptional repressor LfrR (Mycobacterium smegmatis) is a protein target in DrugBank. It is acted on by 1 drug in DrugBank.

Gene name
lfrR
UniProtKB entry
Q58L87TrEMBL
Cellular location
Cytoplasmic
Residues / weight
189 residues · 20,618 Da
Also known as
TetR family transcriptional regulator

Resolves to

Protein
UniProtQ58L87UniProt nameQ58L87_MYCSM
Gene
NCBI Gene4534500GenBank61104877
Pharmacology
KEGGmsh:LI98_30780
Structure
PDB2V57PDB2WGB
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on TetR family transcriptional repressor LfrR, how selective are they, and which programs against it are still in active trials?

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