SRSF protein kinase 2

BE0004323ProteinHumansSRPK2

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation... It is acted on by 3 drugs in DrugBank.

Gene name
SRPK2
UniProtKB entry
P78362Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
688 residues · 77,526 Da
Also known as
2.7.11.1 · Serine/arginine-rich protein-specific kinase 2 · SFRS protein kinase 2 · SR-protein-specific kinase 2

Resolves to

Protein
UniProtP78362UniProt nameSRPK2_HUMAN
Gene
HGNCHGNC:11306NCBI Gene6733GenBank1857944GeneCardsSRPK2
Pharmacology
KEGGhsa:6733
Structure
PDB2X7GPDB5MYVPDB7ZKX
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on SRSF protein kinase 2, how selective are they, and which programs against it are still in active trials?

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