50S ribosomal protein L11

Details

Name
50S ribosomal protein L11
Kind
protein
Synonyms
Not Available
Gene Name
rplK
UniProtKB Entry
P29395Swiss-Prot
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
NCBI Taxonomy ID
243274
Amino acid sequence
>lcl|BSEQ0013018|50S ribosomal protein L11
MAKKVAAQIKLQLPAGKATPAPPVGPALGQHGVNIMEFCKRFNAETADKAGMILPVVITV
YEDKSFTFIIKTPPASFLLKKAAGIEKGSSEPKRKIVGKVTRKQIEEIAKTKMPDLNANS
LEAAMKIIEGTAKSMGIEVVD
Number of residues
141
Molecular Weight
15088.79
Theoretical pI
10.39
GO Classification
Functions
large ribosomal subunit rRNA binding / structural constituent of ribosome
Processes
translation
Components
ribosome
General Function
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
Specific Function
large ribosomal subunit rRNA binding
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0013019|50S ribosomal protein L11 (rplK)
ATGGCGAAGAAAGTAGCGGCTCAGATTAAATTACAACTGCCTGCCGGAAAAGCCACGCCG
GCTCCACCCGTTGGACCCGCCTTGGGTCAGCACGGTGTTAACATCATGGAGTTTTGTAAA
AGGTTCAATGCCGAAACAGCGGATAAAGCAGGCATGATACTTCCTGTTGTTATCACAGTG
TACGAAGACAAGTCGTTCACTTTCATCATCAAAACACCACCTGCTTCCTTCCTTCTCAAG
AAAGCAGCGGGTATAGAGAAGGGTTCTTCCGAGCCAAAAAGAAAGATAGTTGGAAAAGTT
ACCAGAAAACAGATTGAAGAAATAGCGAAAACAAAGATGCCAGATTTGAACGCAAACAGC
TTGGAAGCAGCCATGAAGATCATTGAAGGAACCGCTAAGAGTATGGGAATAGAAGTAGTG
GACTGA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP29395
UniProtKB Entry NameRL11_THEMA
GenBank Protein ID407022
GenBank Gene IDZ11839
PDB ID(s)1IP8, 1JQM, 1JQS, 1JQT, 1MMS, 1MVR, 1OLN, 1PN7, 1PN8, 1R2W, 1R2X, 2BCW, 2GKY, 2GKZ, 2JQ7, 2K3F
KEGG IDtma:TM0454
NCBI Gene ID897484
General References
  1. Liao D, Dennis PP: The organization and expression of essential transcription translation component genes in the extremely thermophilic eubacterium Thermotoga maritima. J Biol Chem. 1992 Nov 15;267(32):22787-97. [Article]
  2. Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
  3. Wimberly BT, Guymon R, McCutcheon JP, White SW, Ramakrishnan V: A detailed view of a ribosomal active site: the structure of the L11-RNA complex. Cell. 1999 May 14;97(4):491-502. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic AcidexperimentalunknowntargetDetails
(4s)-2-[(1e)-1-Aminoprop-1-Enyl]-4,5-Dihydro-1,3-Thiazole-4-Carboxylic AcidexperimentalunknowntargetDetails