Protease 1
Details
- Name
- Protease 1
- Kind
- protein
- Synonyms
- 3.4.21.50
- API
- Lysyl endopeptidase
- Protease I
- Gene Name
- Not Available
- UniProtKB Entry
- P15636Swiss-Prot
- Organism
- Achromobacter lyticus
- NCBI Taxonomy ID
- 224
- Amino acid sequence
>lcl|BSEQ0013030|Protease 1 MKRICGSLLLLGLSISAALAAPASRPAAFDYANLSSVDKVALRTMPAVDVAKAKAEDLQR DKRGDIPRFALAIDVDMTPQNSGAWEYTADGQFAVWRQRVRSEKALSLNFGFTDYYMPAG GRLLVYPATQAPAGDRGLISQYDASNNNSARQLWTAVVPGAEAVIEAVIPRDKVGEFKLR LTKVNHDYVGFGPLARRLAAASGEKGVSGSCNIDVVCPEGDGRRDIIRAVGAYSKSGTLA CTGSLVNNTANDRKMYFLTAHHCGMGTASTAASIVVYWNYQNSTCRAPNTPASGANGDGS MSQTQSGSTVKATYATSDFTLLELNNAANPAFNLFWAGWDRRDQNYPGAIAIHHPNVAEK RISNSTSPTSFVAWGGGAGTTHLNVQWQPSGGVTEPGSSGSPIYSPEKRVLGQLHGGPSS CSATGTNRSDQYGRVFTSWTGGGAAASRLSDWLDPASTGAQFIDGLDSGGGTPNTPPVAN FTSTTSGLTATFTDSSTDSDGSIASRSWNFGDGSTSTATNPSKTYAAAGTYTVTLTVTDN GGATNTKTGSVTVSGGPGAQTYTNDTDVAIPDNATVESPITVSGRTGNGSATTPIQVTIY HTYKSDLKVDLVAPDGTVYNLHNRTGGSAHNIIQTFTKDLSSEAAQRAPGSCG
- Number of residues
- 653
- Molecular Weight
- 68124.56
- Theoretical pI
- 7.26
- GO Classification
- Functionsserine-type endopeptidase activityComponentsextracellular region
- General Function
- Not Available
- Specific Function
- serine-type endopeptidase activity
- Pfam Domain Function
- P_proprotein (PF01483)
- Signal Regions
- 1-20
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0008252|1962 bp ACATCACGGACGGAGACAAGCAATGAAACGCATTTGTGGTTCCCTGCTGTTGCTCGGTTT GTCGATCAGCGCCGCGCTCGCCGCCCCGGCCTCGCGCCCCGCGGCGTTCGATTACGCCAA TCTTTCCAGCGTCGACAAGGTCGCCTTGCGCACCATGCCGGCGGTCGACGTGGCCAAGGC CAAGGCCGAAGATTTGCAGCGCGACAAGCGCGGCGACATCCCGCGCTTCGCCCTGGCGAT CGACGTGGACATGACCCCTCAGAATTCCGGCGCGTGGGAATACACCGCCGACGGCCAGTT CGCCGTATGGCGCCAGCGCGTTCGTTCGGAGAAGGCGCTGTCACTGAACTTCGGTTTCAC CGACTACTACATGCCCGCCGGCGGCCGCCTGCTGGTATATCCGGCGACTCAGGCGCCGGC CGGCGATCGCGGCTTGATCAGCCAGTACGACGCCAGCAACAACAACTCGGCGCGCCAACT GTGGACGGCGGTGGTGCCGGGCGCCGAAGCGGTGATCGAAGCGGTGATCCCGCGCGACAA GGTCGGCGAGTTCAAGCTGCGCCTGACCAAGGTCAACCACGACTACGTCGGTTTCGGCCC GCTCGCGCGCCGCCTGGCCGCTGCGTCCGGCGAGAAGGGCGTGTCGGGTTCGTGCAACAT CGACGTGGTCTGCCCCGAAGGCGACGGCCGCCGCGACATCATCCGCGCGGTCGGTGCGTA CTCGAAGAGCGGCACGCTGGCCTGTACCGGTTCGCTGGTCAACAACACCGCCAACGACCG CAAGATGTACTTCCTGACCGCGCACCACTGCGGCATGGGCACGGCCTCGACCGCCGCGTC GATCGTGGTGTACTGGAACTATCAGAACTCGACCTGCCGCGCGCCCAACACGCCGGCCAG CGGCGCCAACGGCGACGGCTCGATGAGCCAGACCCAGTCGGGTTCGACGGTCAAGGCGAC CTACGCCACCTCCGACTTCACCCTGCTCGAGTTGAACAATGCGGCCAACCCCGCGTTCAA CCTGTTCTGGGCCGGTTGGGACCGTCGCGACCAGAACTATCCCGGCGCGATCGCCATCCA CCATCCCAACGTCGCCGAGAAGCGCATCAGCAACTCCACCAGCCCGACCTCGTTCGTGGC CTGGGGCGGCGGCGCCGGCACCACGCATTTGAACGTGCAGTGGCAGCCCTCGGGCGGCGT GACCGAGCCGGGTTCGTCGGGTTCGCCGATCTACAGCCCGGAAAAGCGCGTGCTCGGCCA GCTGCACGGCGGCCCGTCGAGCTGCAGCGCCACCGGCACCAACCGCAGCGACCAGTACGG CCGCGTGTTCACCTCGTGGACCGGCGGCGGCGCCGCGGCCTCGCGCCTGAGCGATTGGCT CGATCCGGCCAGCACCGGCGCGCAGTTCATCGACGGCCTGGATTCGGGCGGCGGCACGCC GAACACTCCGCCGGTGGCGAACTTCACCTCCACCACCAGCGGCCTGACCGCGACCTTCAC CGACAGCTCCACCGACAGCGACGGTTCGATCGCCTCGCGTAGCTGGAACTTCGGCGACGG CAGCACCTCGACCGCGACCAACCCGAGCAAGACCTACGCCGCGGCGGGCACCTACACCGT CACCCTGACGGTCACCGACAACGGCGGCGCCACCAACACCAAGACCGGTTCGGTCACCGT GTCCGGCGGCCCGGGTGCGCAGACCTACACCAACGACACCGATGTGGCGATCCCGGACAA CGCGACGGTCGAAAGCCCGATCACCGTGTCCGGCCGCACCGGCAACGGCTCGGCGACCAC GCCGATCCAGGTGACGATCTACCACACCTACAAGAGCGATCTGAAGGTGGACCTGGTCGC GCCGGACGGCACCGTCTACAACCTGCACAACCGCACCGGCGGCAGCGCGCACAACATCAT CCAGACCTTCACCAAGGACCTGTCGAGCGAAGCGGCTCAACG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P15636 UniProtKB Entry Name API_ACHLY GenBank Protein ID 141804 GenBank Gene ID J05128 PDB ID(s) 1ARB, 1ARC, 4GPG - General References
- Ohara T, Makino K, Shinagawa H, Nakata A, Norioka S, Sakiyama F: Cloning, nucleotide sequence, and expression of Achromobacter protease I gene. J Biol Chem. 1989 Dec 5;264(34):20625-31. [Article]
- Tsunasawa S, Masaki T, Hirose M, Soejima M, Sakiyama F: The primary structure and structural characteristics of Achromobacter lyticus protease I, a lysine-specific serine protease. J Biol Chem. 1989 Mar 5;264(7):3832-9. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide experimental unknown target Details