Protein S100-A4

BE0004350ProteinHumansS100A4

Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy (PubMed:16707441, PubMed:23752197, PubMed:30713770). It is acted on by 3 drugs in DrugBank.

Gene name
S100A4
UniProtKB entry
P26447Swiss-Prot
Cellular location
Secreted
Residues / weight
101 residues · 11,728 Da
Also known as
Calvasculin · CAPL · Metastasin · MTS1 · Placental calcium-binding protein

Resolves to

Protein
UniProtP26447UniProt nameS10A4_HUMAN
Gene
HGNCHGNC:10494NCBI Gene6275GenBank179917GeneCardsS100A4
Pharmacology
KEGGhsa:6275
Structure
PDB1M31PDB2LNKPDB2MRD
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
17+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Protein S100-A4, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In