Acyl-coenzyme A thioesterase 13

BE0004376ProteinHumansACOT13

Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545). It is acted on by 1 drug in DrugBank.

Gene name
ACOT13
UniProtKB entry
Q9NPJ3Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
140 residues · 14,960 Da
Also known as
3.1.2.- · Acyl-CoA thioesterase 13 · Hotdog-fold thioesterase superfamily member 2 · Palmitoyl-CoA hydrolase · THEM2

Resolves to

Protein
UniProtQ9NPJ3UniProt nameACO13_HUMAN
Gene
HGNCHGNC:20999NCBI Gene55856GenBank7677052GeneCardsACOT13
Pharmacology
KEGGhsa:55856
Structure
PDB2F0XPDB2H4UPDB3F5O
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Acyl-coenzyme A thioesterase 13, and which indications are they being tested in?

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