Thiol:disulfide interchange protein DsbA

BE0004377ProteinEscherichia coli (strain K12)dsbA

Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. It is acted on by 1 drug in DrugBank.

Gene name
dsbA
UniProtKB entry
P0AEG4Swiss-Prot
Cellular location
Periplasm
Residues / weight
208 residues · 23,104 Da
Also known as
dsf · ppfA

Resolves to

Protein
UniProtP0AEG4UniProt nameDSBA_ECOLI
Gene
NCBI Gene948353GenBank762927
Pharmacology
KEGGecj:JW3832
Structure
PDB1A23PDB1A24PDB1A2J
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
20+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Thiol:disulfide interchange protein DsbA, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In