Endoglucanase H

BE0004421ProteinClostridium thermocellum (strain ATCC 27405 / DSM 1237)celH

This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. It is acted on by 1 drug in DrugBank.

Gene name
celH
UniProtKB entry
P16218Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
900 residues · 102,415 Da
Also known as
3.2.1.4 · Cellulase H · EgH · Endo-1,4-beta-glucanase H

Resolves to

Protein
UniProtP16218UniProt nameGUNH_ACET2
Gene
GenBank144774
Pharmacology
KEGGcth:Cthe_1472
Structure
PDB1V0APDB2BV9PDB2BVD
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Endoglucanase H, and which indications are they being tested in?

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