Endoglucanase H
Details
- Name
- Endoglucanase H
- Kind
- protein
- Synonyms
- 3.2.1.4
- Cellulase H
- EgH
- Endo-1,4-beta-glucanase H
- Gene Name
- celH
- UniProtKB Entry
- P16218Swiss-Prot
- Organism
- Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)
- NCBI Taxonomy ID
- 203119
- Amino acid sequence
>lcl|BSEQ0017435|Endoglucanase H MKKRLLVSFLVLSIIVGLLSFQSLGNYNSGLKIGAWVGTQPSESAIKSFQELQGRKLDIV HQFINWSTDFSWVRPYADAVYNNGSILMITWEPWEYNTVDIKNGKADAYITRMAQDMKAY GKEIWLRPLHEANGDWYPWAIGYSSRVNTNETYIAAFRHIVDIFRANGATNVKWVFNVNC DNVGNGTSYLGHYPGDNYVDYTSIDGYNWGTTQSWGSQWQSFDQVFSRAYQALASINKPI IIAEFASAEIGGNKARWITEAYNSIRTSYNKVIAAVWFHENKETDWRINSSPEALAAYRE AIGAGSSNPTPTPTWTSTPPSSSPKAVDPFEMVRKMGMGTNLGNTLEAPYEGSWSKSAME YYFDDFKAAGYKNVRIPVRWDNHTMRTYPYTIDKAFLDRVEQVVDWSLSRGFVTIINSHH DDWIKEDYNGNIERFEKIWEQIAERFKNKSENLLFEIMNEPFGNITDEQIDDMNSRILKI IRKTNPTRIVIIGGGYWNSYNTLVNIKIPDDPYLIGTFHYYDPYEFTHKWRGTWGTQEDM DTVVRVFDFVKSWSDRNNIPVYFGEFAVMAYADRTSRVKWYDFISDAALERGFACSVWDN GVFGSLDNDMAIYNRDTRTFDTEILNALFNPGTYPSYSPKPSPTPRPTKPPVTPAVGEKM LDDFEGVLNWGSYSGEGAKVSTKIVSGKTGNGMEVSYTGTTDGYWGTVYSLPDGDWSKWL KISFDIKSVDGSANEIRFMIAEKSINGVGDGEHWVYSITPDSSWKTIEIPFSSFRRRLDY QPPGQDMSGTLDLDNIDSIHFMYANNKSGKFVVDNIKLIGATSDPTPSIKHGDLNFDNAV NSTDLLMLKRYILKSLELGTSEQEEKFKKAADLNRDNKVDSTDLTILKRYLLKAISEIPI
- Number of residues
- 900
- Molecular Weight
- 102415.005
- Theoretical pI
- 5.26
- GO Classification
- Functionscellulase activityProcessescellulose catabolic process
- General Function
- This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
- Specific Function
- beta-glucosidase activity
- Pfam Domain Function
- Signal Regions
- 1-44
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0017436|Endoglucanase H (celH) ATGAAAAAAAGGCTTTTAGTTTCTTTTTTGGTGTTAAGCATAATTGTAGGATTACTTTCT TTTCAGTCGCTTGGTAATTACAACAGTGGTTTAAAAATCGGTGCTTGGGTGGGAACCCAG CCGTCAGAATCAGCAATTAAGAGTTTTCAGGAACTTCAGGGTAGAAAGCTTGATATTGTC CACCAGTTTATTAACTGGTCAACTGATTTTTCCTGGGTAAGACCTTATGCCGACGCTGTT TATAATAACGGCTCAATATTAATGATTACCTGGGAACCTTGGGAATACAACACTGTAGAT ATCAAAAACGGTAAAGCGGATGCTTACATAACCAGAATGGCGCAAGATATGAAAGCCTAT GGCAAGGAAATTTGGTTAAGACCTCTTCATGAAGCCAACGGAGACTGGTATCCATGGGCC ATAGGATATTCTTCAAGAGTAAACACAAACGAAACTTACATAGCCGCTTTCAGACATATT GTCGATATTTTCCGTGCCAACGGAGCCACCAACGTCAAATGGGTGTTTAATGTAAACTGC GACAATGTAGGTAACGGCACAAGTTATCTGGGTCATTATCCCGGAGATAATTATGTAGAC TACACCTCAATTGACGGATACAACTGGGGTACCACTCAAAGCTGGGGAAGCCAATGGCAA AGCTTTGATCAGGTTTTCTCCAGAGCCTACCAAGCTTTGGCATCAATAAACAAACCCATC ATTATAGCAGAGTTTGCATCAGCTGAAATAGGCGGAAACAAGGCAAGATGGATTACAGAA GCATATAACTCTATAAGAACATCCTACAACAAGGTAATTGCTGCAGTATGGTTTCACGAG AACAAAGAAACCGACTGGAGAATCAACTCAAGTCCTGAAGCCCTTGCAGCATACAGGGAG GCAATAGGAGCCGGTTCATCAAATCCTACCCCTACTCCAACTTGGACCTCTACTCCACCA TCAAGCTCACCAAAGGCTGTCGACCCCTTTGAAATGGTTAGAAAAATGGGTATGGGAACA AACCTCGGAAACACTCTCGAAGCTCCCTATGAAGGCTCCTGGTCCAAGTCTGCCATGGAA TATTATTTTGATGATTTTAAAGCTGCAGGATATAAAAACGTAAGAATCCCTGTAAGATGG GACAACCATACAATGAGGACATACCCGTATACCATTGACAAAGCCTTTTTGGACAGGGTT GAGCAAGTGGTTGACTGGTCACTTTCAAGAGGTTTTGTTACAATTATAAATTCTCACCAT GATGACTGGATCAAGGAAGACTATAACGGAAACATAGAACGGTTTGAAAAGATATGGGAA CAGATTGCGGAAAGGTTTAAAAACAAATCCGAAAATCTTCTGTTTGAAATCATGAATGAG CCTTTCGGTAACATTACAGACGAACAAATAGACGACATGAACAGCAGAATATTAAAAATA ATCAGAAAGACCAATCCAACCCGTATTGTTATAATAGGCGGAGGTTATTGGAACAGTTAT AATACGCTTGTAAACATTAAAATTCCTGATGACCCATACTTAATCGGAACTTTCCATTAC TATGACCCATATGAATTTACTCACAAGTGGAGAGGTACATGGGGTACTCAGGAAGACATG GATACTGTAGTAAGAGTATTTGATTTTGTTAAGAGTTGGTCTGACAGAAACAATATCCCG GTATATTTTGGAGAATTTGCCGTAATGGCTTATGCCGACAGAACTTCCCGTGTAAAATGG TATGATTTTATAAGTGATGCGGCCCTGGAGCGCGGTTTTGCATGTTCCGTATGGGATAAC GGCGTTTTTGGTTCATTGGATAATGACATGGCTATTTACAACAGAGATACCCGTACCTTT GACACTGAAATCCTCAATGCACTATTTAATCCCGGAACATATCCGTCTTATTCTCCGAAA CCTTCACCAACTCCAAGACCGACCAAACCGCCCGTAACACCGGCTGTCGGTGAAAAAATG CTGGATGATTTTGAGGGTGTGTTAAATTGGGGTTCATACTCCGGTGAAGGTGCAAAAGTT TCAACAAAAATTGTGTCCGGAAAAACAGGAAACGGCATGGAAGTCAGCTACACCGGGACA ACGGACGGCTACTGGGGAACAGTATACAGTTTACCGGACGGCGATTGGTCAAAATGGCTT AAAATCTCTTTTGACATTAAGTCCGTTGACGGTTCTGCCAATGAAATCAGATTTATGATT GCTGAAAAAAGCATAAACGGTGTGGGAGACGGAGAACACTGGGTTTACTCAATAACTCCC GACAGTTCGTGGAAAACTATAGAAATACCGTTCTCCAGCTTTAGAAGAAGACTTGATTAT CAGCCGCCTGGACAGGATATGAGCGGTACTTTGGATCTTGACAATATAGATTCAATTCAC TTCATGTATGCCAACAACAAGTCGGGAAAATTTGTCGTAGACAATATCAAGCTGATTGGT GCTACTTCCGATCCGACTCCTTCAATAAAACACGGAGATTTGAACTTCGATAATGCAGTG AATTCTACAGACTTGTTAATGCTTAAAAGGTATATCCTCAAATCTTTGGAACTCGGTACA TCTGAGCAGGAGGAAAAATTCAAAAAAGCGGCAGATTTAAACAGGGACAACAAGGTCGAC TCCACTGACTTGACAATTTTGAAAAGATACTTGCTGAAAGCCATCAGTGAAATACCCATA TAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P16218 UniProtKB Entry Name GUNH_CLOTH GenBank Protein ID 144774 GenBank Gene ID M31903 PDB ID(s) 1V0A, 2BV9, 2BVD, 2CIP, 2CIT, 2LRO, 2LRP, 2V3G, 2VI0, 4U3A, 4U5I, 4U5K KEGG ID cth:Cthe_1472 - General References
- Yague E, Beguin P, Aubert JP: Nucleotide sequence and deletion analysis of the cellulase-encoding gene celH of Clostridium thermocellum. Gene. 1990 Apr 30;89(1):61-7. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details 4-Methylcoumarin experimental unknown target Details