Cytohesin-3

BE0004433ProteinHumansCYTH3

Promotes guanine-nucleotide exchange on ARF1 and ARF6. It is acted on by 3 drugs in DrugBank.

Gene name
CYTH3
UniProtKB entry
O43739Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
400 residues · 46,348 Da
Also known as
ARF nucleotide-binding site opener 3 · ARNO3 · General receptor of phosphoinositides 1 · GRP1 · PH, SEC7 and coiled-coil domain-containing protein 3

Resolves to

Protein
UniProtO43739UniProt nameCYH3_HUMAN
Gene
HGNCHGNC:9504NCBI Gene9265GeneCardsCYTH3
Structure
PDB4KAXPDB6U3EPDB6U3G
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytohesin-3, and which indications are they being tested in?

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