Thiosulfate sulfurtransferase

BE0004455ProteinHumansTST

Catalyzes the transfer of sulfur ion from thiosulfate to cyanide, although other thiol compounds, besides cyanide, can act as sulfur ion acceptors (By similarity). It is acted on by 3 drugs in DrugBank.

Gene name
TST
UniProtKB entry
Q16762Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
297 residues · 33,429 Da
Also known as
2.8.1.1 · Rhodanese

Resolves to

Protein
UniProtQ16762UniProt nameTHTR_HUMAN
Gene
HGNCHGNC:12388NCBI Gene7263GeneCardsTST
Pharmacology
KEGGhsa:7263
Structure
PDB8AGF
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thiosulfate sulfurtransferase, how selective are they, and which programs against it are still in active trials?

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