Beta-enolase

BE0004460ProteinHumansENO3

Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. It is acted on by 4 drugs in DrugBank.

Gene name
ENO3
UniProtKB entry
P13929Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
434 residues · 46,986 Da
Also known as
2-phospho-D-glycerate hydro-lyase · 4.2.1.11 · Enolase 3 · MSE · Muscle-specific enolase

Resolves to

Protein
UniProtP13929UniProt nameENOB_HUMAN
Gene
HGNCHGNC:3354NCBI Gene2027GeneCardsENO3
Pharmacology
KEGGhsa:2027
Structure
PDB2XSX
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Beta-enolase, and which indications are they being tested in?

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