Potassium voltage-gated channel subfamily A member 4

BE0004502ProteinHumansKCNA4

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. It is acted on by 2 drugs in DrugBank.

Gene name
KCNA4
UniProtKB entry
P22459Swiss-Prot
Cellular location
Cell membrane
Residues / weight
653 residues · 73,257 Da
Also known as
HPCN2 · KCNA4L · Voltage-gated K(+) channel HuKII · Voltage-gated potassium channel HBK4 · Voltage-gated potassium channel HK1

Resolves to

Protein
UniProtP22459UniProt nameKCNA4_HUMAN
Gene
HGNCHGNC:6222NCBI Gene3739GeneCardsKCNA4
Pharmacology
KEGGhsa:3739
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium voltage-gated channel subfamily A member 4, how selective are they, and which programs against it are still in active trials?

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