Trypsin-2

BE0004529ProteinHumansPRSS2

In the ileum, may be involved in defensin processing, including DEFA5. It is acted on by 7 drugs in DrugBank.

Gene name
PRSS2
UniProtKB entry
P07478Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
247 residues · 26,488 Da
Also known as
3.4.21.4 · Anionic trypsinogen · Serine protease 2 · TRY2 · TRYP2

Resolves to

Protein
UniProtP07478UniProt nameTRY2_HUMAN
Gene
HGNCHGNC:9483NCBI Gene5645GeneCardsPRSS2
Pharmacology
KEGGhsa:5645
Structure
PDB7Z9F
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Trypsin-2, and which indications are they being tested in?

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