Adenylate kinase 8

BE0004536ProteinHumansAK8

Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. It is acted on by 1 drug in DrugBank.

Gene name
AK8
UniProtKB entry
Q96MA6Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
479 residues · 54,925 Da
Also known as
2.7.4.3 · 2.7.4.6 · AK 8 · ATP-AMP transphosphorylase 8 · C9orf98

Resolves to

Protein
UniProtQ96MA6UniProt nameKAD8_HUMAN
Gene
HGNCHGNC:26526NCBI Gene158067GeneCardsAK8
Pharmacology
KEGGhsa:158067
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Adenylate kinase 8, and which indications are they being tested in?

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