Gamma-enolase

BE0004550ProteinHumansENO2

Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
ENO2
UniProtKB entry
P09104Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
434 residues · 47,268 Da
Also known as
2-phospho-D-glycerate hydro-lyase · 4.2.1.11 · Enolase 2 · Neural enolase · Neuron-specific enolase

Resolves to

Protein
UniProtP09104UniProt nameENOG_HUMAN
Gene
HGNCHGNC:3353NCBI Gene2026GeneCardsENO2
Pharmacology
KEGGhsa:2026
Structure
PDB1TE6PDB2AKMPDB2AKZ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
11Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
16+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Gamma-enolase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In