N-acylneuraminate cytidylyltransferase

BE0004564ProteinHumansCMAS

Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. It is acted on by 1 drug in DrugBank.

Gene name
CMAS
UniProtKB entry
Q8NFW8Swiss-Prot
Cellular location
Nucleus
Residues / weight
434 residues · 48,379 Da
Also known as
2.7.7.43 · CMP-N-acetylneuraminic acid synthase · CMP-NeuNAc synthase

Resolves to

Protein
UniProtQ8NFW8UniProt nameNEUA_HUMAN
Gene
HGNCHGNC:18290NCBI Gene55907GeneCardsCMAS
Pharmacology
KEGGhsa:55907
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on N-acylneuraminate cytidylyltransferase, and which indications are they being tested in?

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