Pantothenate synthetase
Details
- Name
- Pantothenate synthetase
- Kind
- protein
- Synonyms
- 6.3.2.1
- Pantoate--beta-alanine ligase
- Pantoate-activating enzyme
- PS
- Gene Name
- panC
- UniProtKB Entry
- Q5SHF5Swiss-Prot
- Organism
- Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
- NCBI Taxonomy ID
- 300852
- Amino acid sequence
>lcl|BSEQ0013192|Pantothenate synthetase MRTVSTVAELRAALPREGVGFVPTMGYLHRGHLALVERARRENPFVVVSVFVNPLQFGPG EDYHRYPRDLERDRALLQEAGVDLLFAPGVEEMYPEGFATRVQVEGPLTALWEGAVRPGH FQGVATVVARLFLLVQPQRAYFGEKDYQQLLVVRRMVRDLGFPVEVVGVPTVREEDGLAL SSRNVYLSPETRKKAPVLYRALLAMREVAGQGGSVAEALRAGEEALRAVPEFRKDYLAIV HPETLLPLSDWVAGARGIVAGRFPEARLIDNLEVYP
- Number of residues
- 276
- Molecular Weight
- 30695.125
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / pantoate-beta-alanine ligase activityProcessespantothenate biosynthetic processComponentscytoplasm
- General Function
- Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
- Specific Function
- ATP binding
- Pfam Domain Function
- Pantoate_ligase (PF02569)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0013193|Pantothenate synthetase (panC) GTGAGAACCGTGAGCACCGTGGCCGAGCTGCGGGCGGCCCTGCCCCGGGAGGGCGTGGGC TTCGTCCCCACCATGGGCTACCTCCACCGGGGGCACCTCGCCCTGGTGGAACGGGCCCGG CGGGAGAACCCCTTCGTGGTGGTCTCCGTCTTCGTCAACCCCCTCCAGTTCGGCCCCGGG GAGGACTACCACCGCTACCCCCGGGACCTGGAGCGGGACCGGGCCCTTTTGCAGGAGGCG GGGGTGGACCTCCTCTTCGCCCCCGGCGTGGAGGAGATGTACCCCGAGGGCTTCGCCACC CGGGTCCAGGTGGAGGGTCCCCTCACCGCCCTTTGGGAGGGGGCGGTGCGCCCCGGCCAC TTCCAGGGGGTGGCCACGGTGGTGGCGCGGCTTTTCCTTTTGGTCCAGCCCCAGAGGGCC TACTTCGGGGAGAAGGACTACCAGCAGCTCCTCGTGGTGCGGCGGATGGTCCGGGACCTG GGCTTCCCCGTGGAGGTGGTGGGGGTGCCCACGGTGCGGGAGGAGGACGGCCTCGCCCTT TCCAGCCGCAACGTCTACCTCTCCCCCGAGACCCGCAAGAAGGCCCCCGTGCTCTACCGG GCCCTCCTGGCCATGCGGGAGGTGGCGGGGCAGGGGGGAAGCGTGGCCGAGGCGCTCCGG GCGGGAGAGGAGGCTTTGCGGGCGGTGCCCGAGTTCCGCAAGGACTACCTCGCCATCGTC CACCCCGAGACCCTCCTGCCCCTCTCCGACTGGGTCGCGGGGGCCAGGGGGATCGTGGCC GGGAGGTTCCCCGAGGCGCGGCTTATAGACAACCTGGAGGTCTACCCATGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q5SHF5 UniProtKB Entry Name PANC_THET8 PDB ID(s) 1UFV, 1V8F KEGG ID ttj:TTHA1775 NCBI Gene ID 3169469 - General References
- Not Available
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Tris-Hydroxymethyl-Methyl-Ammonium experimental unknown target Details