Pantothenate synthetase

BE0004567ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)panC

Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. It is acted on by 1 drug in DrugBank.

Gene name
panC
UniProtKB entry
Q5SHF5Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
276 residues · 30,695 Da
Also known as
6.3.2.1 · Pantoate--beta-alanine ligase · Pantoate-activating enzyme · PS

Resolves to

Protein
UniProtQ5SHF5UniProt namePANC_THET8
Gene
NCBI Gene3169469
Pharmacology
KEGGttj:TTHA1775
Structure
PDB1UFVPDB1V8F
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Pantothenate synthetase, and which indications are they being tested in?

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