14-3-3 protein epsilon

BE0004570ProteinHumansYWHAE

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:21189250). It is acted on by 2 drugs in DrugBank.

Gene name
YWHAE
UniProtKB entry
P62258Swiss-Prot
Cellular location
Nucleus
Residues / weight
255 residues · 29,174 Da
Also known as
14-3-3E

Resolves to

Protein
UniProtP62258UniProt name1433E_HUMAN
Gene
HGNCHGNC:12851NCBI Gene7531GeneCardsYWHAE
Pharmacology
KEGGhsa:7531
Structure
PDB2BR9PDB3UALPDB3UBW
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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29GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 14-3-3 protein epsilon, and which indications are they being tested in?

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