Transitional endoplasmic reticulum ATPase

BE0004572ProteinHumansVCP

Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. It is acted on by 5 drugs in DrugBank.

Gene name
VCP
UniProtKB entry
P55072Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
806 residues · 89,321 Da
Also known as
15S Mg(2+)-ATPase p97 subunit · 3.6.4.6 · HEL-220 · HEL-S-70 · TER ATPase

Resolves to

Protein
UniProtP55072UniProt nameTERA_HUMAN
Gene
HGNCHGNC:12666NCBI Gene7415GeneCardsVCP
Pharmacology
KEGGhsa:7415
Structure
PDB10QQPDB10QRPDB11TA
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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49GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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66+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Transitional endoplasmic reticulum ATPase, and which indications are they being tested in?

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