Rho-related GTP-binding protein RhoE

BE0004602ProteinHumansRND3

Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. It is acted on by 1 drug in DrugBank.

Gene name
RND3
UniProtKB entry
P61587Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
244 residues · 27,368 Da
Also known as
3.6.5.2 · ARHE · Protein MemB · Rho family GTPase 3 · Rho-related GTP-binding protein Rho8

Resolves to

Protein
UniProtP61587UniProt nameRND3_HUMAN
Gene
HGNCHGNC:671NCBI Gene390GeneCardsRND3
Pharmacology
KEGGhsa:390
Structure
PDB1M7BPDB2V55PDB4BG6
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Rho-related GTP-binding protein RhoE, and which indications are they being tested in?

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