Deoxyribose-phosphate aldolase

BE0004607ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)deoC

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. It is acted on by 1 drug in DrugBank.

Gene name
deoC
UniProtKB entry
Q5SJ28Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
220 residues · 23,307 Da
Also known as
2-deoxy-D-ribose 5-phosphate aldolase · 4.1.2.4 · Deoxyriboaldolase · DERA · Phosphodeoxyriboaldolase

Resolves to

Protein
UniProtQ5SJ28UniProt nameDEOC_THET8
Gene
NCBI Gene3169004
Pharmacology
KEGGttj:TTHA1186
Structure
PDB1J2WPDB1UB3
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Deoxyribose-phosphate aldolase, and which indications are they being tested in?

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