Gamma-glutamylaminecyclotransferase

BE0004623ProteinHumansGGACT

Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. It is acted on by 1 drug in DrugBank.

Gene name
GGACT
UniProtKB entry
Q9BVM4Swiss-Prot
Residues / weight
153 residues · 17,328 Da
Also known as
4.3.2.8 · A2LD1 · AIG2-like domain-containing protein 1 · Gamma-glutamylamine cyclotransferase · GGACT

Resolves to

Protein
UniProtQ9BVM4UniProt nameGGACT_HUMAN
Gene
HGNCHGNC:25100NCBI Gene87769GeneCardsGGACT
Pharmacology
KEGGhsa:87769
Structure
PDB3JUBPDB3JUCPDB3JUD
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Gamma-glutamylaminecyclotransferase, how selective are they, and which programs against it are still in active trials?

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