Large ribosomal subunit protein uL16

BE0004650ProteinEscherichia coli (strain K12)rplP

This protein binds directly to 23S ribosomal RNA and is located at the A site of the peptidyltransferase center. It is acted on by 1 drug in DrugBank.

Gene name
rplP
UniProtKB entry
P0ADY7Swiss-Prot
Residues / weight
136 residues · 15,281 Da
Also known as
50S ribosomal protein L16

Resolves to

Protein
UniProtP0ADY7UniProt nameRL16_ECOLI
Gene
NCBI Gene947806
Pharmacology
KEGGecj:JW3275
Structure
PDB2J28PDB2RDOPDB3BBX
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Large ribosomal subunit protein uL16, how selective are they, and which programs against it are still in active trials?

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