Equilibrative nucleoside transporter 2

BE0004706ProteinHumansSLC29A2

Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis (PubMed:10722669, PubMed:12527552, PubMed:12590919, PubMed:16214850, PubMed:21795683, PubMed:9396714, PubMed:9478986). It is acted on by 13 drugs in DrugBank.

Gene name
SLC29A2
UniProtKB entry
Q14542Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
456 residues · 50,112 Da
Also known as
36 kDa nucleolar protein HNP36 · Delayed-early response protein 12 · DER12 · ENT2 · Equilibrative NBMPR-insensitive nucleoside transporter

Resolves to

Protein
UniProtQ14542UniProt nameS29A2_HUMAN
Gene
HGNCHGNC:11004NCBI Gene3177GeneCardsSLC29A2
Pharmacology
KEGGhsa:3177
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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28GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Equilibrative nucleoside transporter 2, how selective are they, and which programs against it are still in active trials?

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