Potassium voltage-gated channel subfamily A member 2

BE0004715ProteinHumansKCNA2

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. It is acted on by 2 drugs in DrugBank.

Gene name
KCNA2
UniProtKB entry
P16389Swiss-Prot
Cellular location
Cell membrane
Residues / weight
499 residues · 56,716 Da
Also known as
NGK1 · Voltage-gated K(+) channel HuKIV · Voltage-gated potassium channel HBK5 · Voltage-gated potassium channel subunit Kv1.2

Resolves to

Protein
UniProtP16389UniProt nameKCNA2_HUMAN
Gene
HGNCHGNC:6220NCBI Gene3737GeneCardsKCNA2
Pharmacology
IUPHAR/GtoPdb539KEGGhsa:3737
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium voltage-gated channel subfamily A member 2, how selective are they, and which programs against it are still in active trials?

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