Potassium voltage-gated channel subfamily A member 3

BE0004716ProteinHumansKCNA3

Mediates the voltage-dependent potassium ion permeability of excitable membranes. It is acted on by 3 drugs in DrugBank.

Gene name
KCNA3
UniProtKB entry
P22001Swiss-Prot
Cellular location
Cell membrane
Residues / weight
575 residues · 63,841 Da
Also known as
HGK5 · HLK3 · HPCN3 · Voltage-gated K(+) channel HuKIII · Voltage-gated potassium channel subunit Kv1.3

Resolves to

Protein
UniProtP22001UniProt nameKCNA3_HUMAN
Gene
HGNCHGNC:6221NCBI Gene3738GeneCardsKCNA3
Pharmacology
IUPHAR/GtoPdb540KEGGhsa:3738
Structure
PDB4BGCPDB7EJ1PDB7EJ2
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium voltage-gated channel subfamily A member 3, how selective are they, and which programs against it are still in active trials?

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