Potassium voltage-gated channel subfamily B member 2

BE0004722ProteinHumansKCNB2

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells. It is acted on by 1 drug in DrugBank.

Gene name
KCNB2
UniProtKB entry
Q92953Swiss-Prot
Cellular location
Cell membrane
Residues / weight
911 residues · 102,562 Da
Also known as
Voltage-gated potassium channel subunit Kv2.2

Resolves to

Protein
UniProtQ92953UniProt nameKCNB2_HUMAN
Gene
HGNCHGNC:6232NCBI Gene9312GeneCardsKCNB2
Pharmacology
IUPHAR/GtoPdb547KEGGhsa:9312
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium voltage-gated channel subfamily B member 2, how selective are they, and which programs against it are still in active trials?

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