Voltage-gated potassium channel KCNC3

BE0004725ProteinHumansKCNC3

Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. It is acted on by 1 drug in DrugBank.

Gene name
KCNC3
UniProtKB entry
Q14003Swiss-Prot
Cellular location
Cell membrane
Residues / weight
757 residues · 80,577 Da
Also known as
KSHIIID · Potassium voltage-gated channel subfamily C member 3 · Voltage-gated potassium channel subunit Kv3.3

Resolves to

Protein
UniProtQ14003UniProt nameKCNC3_HUMAN
Gene
HGNCHGNC:6235NCBI Gene3748GeneCardsKCNC3
Pharmacology
KEGGhsa:3748
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-gated potassium channel KCNC3, how selective are they, and which programs against it are still in active trials?

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