A-type voltage-gated potassium channel KCND1

BE0004726ProteinHumansKCND1

A-type voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes in the brain (PubMed:15454437). It is acted on by 1 drug in DrugBank.

Gene name
KCND1
UniProtKB entry
Q9NSA2Swiss-Prot
Cellular location
Cell membrane
Residues / weight
647 residues · 71,330 Da
Also known as
Potassium voltage-gated channel subfamily D member 1 · Shal-type potassium channel KCND1 · Voltage-gated potassium channel subunit Kv4.1

Resolves to

Protein
UniProtQ9NSA2UniProt nameKCND1_HUMAN
Gene
HGNCHGNC:6237NCBI Gene3750GeneCardsKCND1
Pharmacology
IUPHAR/GtoPdb552KEGGhsa:3750
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on A-type voltage-gated potassium channel KCND1, how selective are they, and which programs against it are still in active trials?

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