Cytochrome P450 4F12

BE0004729ProteinHumansCYP4F12

A cytochrome P450 monooxygenase involved in the metabolism of endogenous polyunsaturated fatty acids (PUFAs). It is acted on by 2 drugs in DrugBank.

Gene name
CYP4F12
UniProtKB entry
Q9HCS2Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
524 residues · 60,308 Da
Also known as
1.14.14.1 · CYPIVF12

Resolves to

Protein
UniProtQ9HCS2UniProt nameCP4FC_HUMAN
Gene
HGNCHGNC:18857NCBI Gene66002GeneCardsCYP4F12
Pharmacology
IUPHAR/GtoPdb1348KEGGhsa:66002
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome P450 4F12, how selective are they, and which programs against it are still in active trials?

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