ATP synthase subunit c

BE0004748ProteinMycobacterium tuberculosisatpE

F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. It is acted on by 3 drugs in DrugBank.

Gene name
atpE
UniProtKB entry
P9WPS1Swiss-Prot
Cellular location
Cell membrane
Residues / weight
81 residues · 8,055 Da
Also known as
ATP synthase F(0) sector subunit c · F-ATPase subunit c · F-type ATPase subunit c · Lipid-binding protein

Resolves to

Protein
UniProtP9WPS1UniProt nameATPL_MYCTU
Gene
NCBI Gene29697275
Pharmacology
KEGGmtu:Rv1305
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ATP synthase subunit c, how selective are they, and which programs against it are still in active trials?

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