Cytochrome P450 2A1

BE0004762ProteinRatCyp2a1

Highly active in the 7-alpha-hydroxylation of testosterone, progesterone and androstenedione. It is acted on by 2 drugs in DrugBank.

Gene name
Cyp2a1
UniProtKB entry
P11711Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
492 residues · 55,995 Da
Also known as
1.14.14.1 · Cyp2a-1 · CYPIIA1 · Cytochrome P450-UT-F · Steroid hormones 7-alpha-hydroxylase

Resolves to

Protein
UniProtP11711UniProt nameCP2A1_RAT
Gene
NCBI Gene24894
Pharmacology
KEGGrno:24894
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome P450 2A1, how selective are they, and which programs against it are still in active trials?

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