Calcium-activated potassium channel subunit alpha-1

BE0004784ProteinMouseKcnma1

Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is acted on by 1 drug in DrugBank.

Gene name
Kcnma1
UniProtKB entry
Q08460Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,209 residues · 134,395 Da
Also known as
BK channel · BKCA alpha · Calcium-activated potassium channel, subfamily M subunit alpha-1 · K(VCA)alpha · KCa1.1

Resolves to

Protein
UniProtQ08460UniProt nameKCMA1_MOUSE
Gene
NCBI Gene16531
Pharmacology
IUPHAR/GtoPdb380
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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44GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Calcium-activated potassium channel subunit alpha-1, and which indications are they being tested in?

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