Actin, aortic smooth muscle

BE0005076ProteinHumansACTA2

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. It is acted on by 1 drug in DrugBank.

Gene name
ACTA2
UniProtKB entry
P62736Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
377 residues · 42,009 Da
Also known as
3.6.4.- · ACTSA · ACTVS · Alpha-actin-2 · Cell growth-inhibiting gene 46 protein

Resolves to

Protein
UniProtP62736UniProt nameACTA_HUMAN
Gene
HGNCHGNC:130NCBI Gene59GeneCardsACTA2
Pharmacology
KEGGhsa:59
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Actin, aortic smooth muscle, and which indications are they being tested in?

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