Histone H2B type 1-C/E/F/G/I

BE0005156ProteinHumansH2BC4

Core component of nucleosome. It is acted on by 1 drug in DrugBank.

Gene name
H2BC4
UniProtKB entry
P62807Swiss-Prot
Cellular location
Nucleus
Residues / weight
126 residues · 13,906 Da
Also known as
H2B/a · H2B/g · H2B/h · H2B/k · H2B/l

Resolves to

Protein
UniProtP62807UniProt nameH2B1C_HUMAN
Gene
HGNCHGNC:4746NCBI Gene8347GeneCardsH2BC8
Pharmacology
KEGGhsa:8347
Structure
PDB10XZPDB10YAPDB10YB
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Histone H2B type 1-C/E/F/G/I, how selective are they, and which programs against it are still in active trials?

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