DAN domain family member 5

BE0005538ProteinHumansDAND5

Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
DAND5
UniProtKB entry
Q8N907Swiss-Prot
Cellular location
Secreted
Residues / weight
189 residues · 20,180 Da
Also known as
CER2 · Cerberus-like protein 2 · Cerl-2 · CKTSF1B3 · COCO

Resolves to

Protein
UniProtQ8N907UniProt nameDAND5_HUMAN
Gene
HGNCHGNC:26780NCBI Gene199699GeneCardsDAND5
Pharmacology
KEGGhsa:199699
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on DAN domain family member 5, how selective are they, and which programs against it are still in active trials?

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