Cytochrome c oxidase assembly factor SCO1

BE0005818ProteinHumansSCO1

Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). It is acted on by 1 drug in DrugBank.

Gene name
SCO1
UniProtKB entry
O75880Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
301 residues · 33,814 Da
Also known as
SCOD1

Resolves to

Protein
UniProtO75880UniProt nameSCO1_HUMAN
Gene
HGNCHGNC:10603NCBI Gene6341GeneCardsSCO1
Pharmacology
KEGGhsa:6341
Structure
PDB1WP0PDB2GGTPDB2GQK
Drugs

What you can answer from here — as of June 05, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome c oxidase assembly factor SCO1, how selective are they, and which programs against it are still in active trials?

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