Hephaestin

BE0008687ProteinHumansHEPH

Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. It is acted on by 2 drugs in DrugBank.

Gene name
HEPH
UniProtKB entry
Q9BQS7Swiss-Prot
Cellular location
Basolateral cell membrane
Residues / weight
1,158 residues · 130,448 Da
Also known as
1.16.3.1 · Hp · KIAA0698

Resolves to

Protein
UniProtQ9BQS7UniProt nameHEPH_HUMAN
Gene
HGNCHGNC:4866NCBI Gene9843GeneCardsHEPH
Pharmacology
KEGGhsa:9843
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Hephaestin, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In