Apolipoprotein C-II

BE0008879ProteinHumansAPOC2

Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. It is acted on by 1 drug in DrugBank.

Gene name
APOC2
UniProtKB entry
P02655Swiss-Prot
Cellular location
Secreted
Residues / weight
101 residues · 11,284 Da
Also known as
APC2 · Apo-CII · ApoC-II · Apolipoprotein C2

Resolves to

Protein
UniProtP02655UniProt nameAPOC2_HUMAN
Gene
HGNCHGNC:609NCBI Gene344GeneCardsAPOC2
Pharmacology
KEGGhsa:344
Structure
PDB1BY6PDB1I5JPDB1O8T
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Apolipoprotein C-II, how selective are they, and which programs against it are still in active trials?

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