Apolipoprotein C-III

BE0008880ProteinHumansAPOC3

Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). It is acted on by 4 drugs in DrugBank.

Gene name
APOC3
UniProtKB entry
P02656Swiss-Prot
Cellular location
Secreted
Residues / weight
99 residues · 10,852 Da
Also known as
Apo-CIII · ApoC-III · Apolipoprotein C3

Resolves to

Protein
UniProtP02656UniProt nameAPOC3_HUMAN
Gene
HGNCHGNC:610NCBI Gene345GeneCardsAPOC3
Pharmacology
KEGGhsa:345
Structure
PDB2JQ3
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Apolipoprotein C-III, how selective are they, and which programs against it are still in active trials?

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