60 kDa heat shock protein, mitochondrial

BE0008956ProteinHumansHSPD1

Chaperonin implicated in mitochondrial protein import and macromolecular assembly. It is acted on by 3 drugs in DrugBank.

Gene name
HSPD1
UniProtKB entry
P10809Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
573 residues · 61,054 Da
Also known as
5.6.1.7 · 60 kDa chaperonin · Chaperonin 60 · CPN60 · Heat shock protein 60

Resolves to

Protein
UniProtP10809UniProt nameCH60_HUMAN
Gene
HGNCHGNC:5261NCBI Gene3329GeneCardsHSPD1
Pharmacology
KEGGhsa:3329
Structure
PDB4PJ1PDB6HT7PDB6MRC
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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41+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 60 kDa heat shock protein, mitochondrial, how selective are they, and which programs against it are still in active trials?

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