Cell growth-regulating nucleolar protein

BE0008958ProteinMouseLyar

Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
Lyar
UniProtKB entry
Q08288Swiss-Prot
Cellular location
Nucleus
Residues / weight
388 residues · 43,735 Da
Also known as
Ly1 antibody-reactive protein · MLZ-264 · Protein expressed in male leptotene and zygotene spermatocytes 264

Resolves to

Protein
UniProtQ08288UniProt nameLYAR_MOUSE
Gene
NCBI Gene17089
Pharmacology
KEGGmmu:17089
Structure
PDB1WJV
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cell growth-regulating nucleolar protein, how selective are they, and which programs against it are still in active trials?

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