Cobalt-precorrin-5B C(1)-methyltransferase

BE0008963ProteinTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)cbiD

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. It is acted on by 1 drug in DrugBank.

Gene name
cbiD
UniProtKB entry
P61987Swiss-Prot
Residues / weight
363 residues · 39,699 Da
Also known as
2.1.1.195 · Cobalt-precorrin-6A synthase

Resolves to

Protein
UniProtP61987UniProt nameCBID_TREDE
Gene
NCBI Gene2739792
Pharmacology
KEGGtde:TDE1595
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cobalt-precorrin-5B C(1)-methyltransferase, how selective are they, and which programs against it are still in active trials?

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