Heterogeneous nuclear ribonucleoprotein L

BE0008964ProteinHumansHNRNPL

Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. It is acted on by 1 drug in DrugBank.

Gene name
HNRNPL
UniProtKB entry
P14866Swiss-Prot
Cellular location
Nucleus, nucleoplasm
Residues / weight
589 residues · 64,132 Da
Also known as
hnRNP L · HNRPL

Resolves to

Protein
UniProtP14866UniProt nameHNRPL_HUMAN
Gene
HGNCHGNC:5045NCBI Gene3191GeneCardsHNRNPL
Pharmacology
KEGGhsa:3191
Structure
PDB3R27PDB3TO8PDB7EVR
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Heterogeneous nuclear ribonucleoprotein L, how selective are they, and which programs against it are still in active trials?

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