Proteasome activator complex subunit 1

BE0008976ProteinHumansPSME1

Implicated in immunoproteasome assembly and required for efficient antigen processing. It is acted on by 1 drug in DrugBank.

Gene name
PSME1
UniProtKB entry
Q06323Swiss-Prot
Residues / weight
249 residues · 28,723 Da
Also known as
11S regulator complex subunit alpha · Activator of multicatalytic protease subunit 1 · IFI5111 · IGUP I-5111 · Interferon gamma up-regulated I-5111 protein

Resolves to

Protein
UniProtQ06323UniProt namePSME1_HUMAN
Gene
HGNCHGNC:9568NCBI Gene5720GeneCardsPSME1
Pharmacology
KEGGhsa:5720
Structure
PDB1AVOPDB7DR6PDB7DRW
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Proteasome activator complex subunit 1, how selective are they, and which programs against it are still in active trials?

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