Trefoil factor 1

BE0008981ProteinHumansTFF1

Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. It is acted on by 2 drugs in DrugBank.

Gene name
TFF1
UniProtKB entry
P04155Swiss-Prot
Cellular location
Secreted
Residues / weight
84 residues · 9,149 Da
Also known as
BCEI · Breast cancer estrogen-inducible protein · hP1.A · PNR-2 · Polypeptide P1.A

Resolves to

Protein
UniProtP04155UniProt nameTFF1_HUMAN
Gene
HGNCHGNC:11755NCBI Gene7031GeneCardsTFF1
Pharmacology
KEGGhsa:7031
Structure
PDB1HI7PDB1PS2PDB6V1D
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Trefoil factor 1, how selective are they, and which programs against it are still in active trials?

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